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HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection

BACKGROUND & AIMS: Current therapies for chronic hepatitis B virus (HBV) infection control viral replication but do not eliminate the risk of progression to hepatocellular carcinoma. HBV-specific CD8 T cells are necessary for viral control, but they are rare and exhausted during chronic infectio...

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Detalles Bibliográficos
Autores principales:	Ferrando-Martinez, Sara, Huang, Kelly, Bennett, Angie Snell, Sterba, Patricia, Yu, Li, Suzich, JoAnn A., Janssen, Harry L.A., Robbins, Scott H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001560/ https://www.ncbi.nlm.nih.gov/pubmed/32039367 http://dx.doi.org/10.1016/j.jhepr.2019.06.001

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