Liver homing of clinical grade Tregs after therapeutic infusion in patients with autoimmune hepatitis

Autoimmune hepatitis (AIH) is an immune-mediated disease with no curative treatment. Regulatory T cell (Treg) therapy is potentially curative in AIH given the critical role of Tregs in preventing autoimmunity. To work effectively, adoptively transferred Tregs must migrate to and survive within the i...

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Detalles Bibliográficos
Autores principales: Oo, Ye Htun, Ackrill, Susan, Cole, Richard, Jenkins, Lee, Anderson, Philip, Jeffery, Hannah C., Jones, Nicholas, Jeffery, Louisa E., Lutz, Philipp, Wawman, Rebecca E., Athwal, Amrita Kaur, Thompson, Jacqui, Gray, Joanna, Guo, Kathy, Barton, Darren, Hirschfield, Gideon M, Wong, Timothy, Guest, Peter, Adams, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001578/
https://www.ncbi.nlm.nih.gov/pubmed/32039380
http://dx.doi.org/10.1016/j.jhepr.2019.08.001

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