Evolutionary analysis of the most polymorphic gene family in falciparum malaria

The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic. Here we have assembled nearly complete var gene repertoires from 2398 field isolates and analysed a normalised set...

Descripción completa

Detalles Bibliográficos
Autores principales: Otto, Thomas D., Assefa, Sammy A., Böhme, Ulrike, Sanders, Mandy J., Kwiatkowski, Dominic, Berriman, Matt, Newbold, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001760/
https://www.ncbi.nlm.nih.gov/pubmed/32055709
http://dx.doi.org/10.12688/wellcomeopenres.15590.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001760/
https://www.ncbi.nlm.nih.gov/pubmed/32055709
http://dx.doi.org/10.12688/wellcomeopenres.15590.1

Ejemplares similares