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Overexpression of p-Akt, p-mTOR and p-eIF4E proteins associates with metastasis and unfavorable prognosis in non-small cell lung cancer

The Akt (protein kinase B)/mammalian target of rapamycin (mTOR) pathway, which is dysregulated in various cancers, controls the assembly of eukaryotic translation initiation factor 4F (eIF4E) complex. However, whether aberrant expression of phosphorylated Akt (p-Akt), phosphorylated mTOR (p-mTOR) an...

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Detalles Bibliográficos
Autores principales:	Lu, Junmi, Zang, Hongjing, Zheng, Hongmei, Zhan, Yuting, Yang, Yang, Zhang, Yuting, Liu, Sile, Feng, Juan, Wen, Qiuyuan, Long, Mengping, Fan, Songqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001968/ https://www.ncbi.nlm.nih.gov/pubmed/32023262 http://dx.doi.org/10.1371/journal.pone.0227768

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