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Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation
Makorins are evolutionary conserved proteins that contain C(3)H-type zinc finger modules and a RING E3 ubiquitin ligase domain. In Drosophila, maternal Makorin 1 (Mkrn1) has been linked to embryonic patterning but the mechanism remained unsolved. Here, we show that Mkrn1 is essential for axis specif...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001992/ https://www.ncbi.nlm.nih.gov/pubmed/31978041 http://dx.doi.org/10.1371/journal.pgen.1008581 |