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Putting an end to the Pseudomonas aeruginosa IQS controversy

Despite published evidence that IQS (2‐(2‐hydroxylphenyl)‐thiazole‐4‐carbaldehyde) is in fact aeruginaldehyde, a by‐product of the siderophore pyochelin biosynthesis or degradation and that the ambABCDE genes are not responsible for IQS synthesis, several authors, including in top review journals, p...

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Detalles Bibliográficos
Autor principal: Cornelis, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002111/
https://www.ncbi.nlm.nih.gov/pubmed/31667921
http://dx.doi.org/10.1002/mbo3.962
Descripción
Sumario:Despite published evidence that IQS (2‐(2‐hydroxylphenyl)‐thiazole‐4‐carbaldehyde) is in fact aeruginaldehyde, a by‐product of the siderophore pyochelin biosynthesis or degradation and that the ambABCDE genes are not responsible for IQS synthesis, several authors, including in top review journals, perpetuate the wrong information. I hope that this short comment will clarify the situation once and for all.