The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward

Genome-wide association studies (GWAS) have identified more than 250 loci associated with body mass index (BMI) and obesity. However, post-GWAS functional genomic investigations have been inadequate for understanding how these genetic loci physiologically impact disease development. We performed a P...

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Detalles Bibliográficos
Autores principales: Ndiaye, Fatou K, Huyvaert, Marlène, Ortalli, Ana, Canouil, Mickaël, Lecoeur, Cécile, Verbanck, Marie, Lobbens, Stéphane, Khamis, Amna, Marselli, Lorella, Marchetti, Piero, Kerr-Conte, Julie, Pattou, François, Marre, Michel, Roussel, Ronan, Balkau, Beverley, Froguel, Philippe, Bonnefond, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002163/
https://www.ncbi.nlm.nih.gov/pubmed/31388097
http://dx.doi.org/10.1038/s41366-019-0428-7

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