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HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer
Prostate cancer is the most common malignancy in men in developed countries. Overexpression of enhancer of zeste homolog 2 (EZH2), the major histone H3 lysine 27 methyltransferase, has been connected to prostate cancer malignancy. However, its downstream genes and pathways have not been well establi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002300/ https://www.ncbi.nlm.nih.gov/pubmed/31636385 http://dx.doi.org/10.1038/s41388-019-1065-2 |