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EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System

Pathogenic mycobacteria encounter multiple environments during macrophage infection. Temporally, the bacteria are engulfed into the phagosome, lyse the phagosomal membrane, and interact with the cytosol before spreading to another cell. Virulence factors secreted by the mycobacterial ESX-1 (ESAT-6-s...

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Detalles Bibliográficos
Autores principales: Sanchez, Kevin G., Ferrell, Micah J., Chirakos, Alexandra E., Nicholson, Kathleen R., Abramovitch, Robert B., Champion, Matthew M., Champion, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002343/
https://www.ncbi.nlm.nih.gov/pubmed/32019792
http://dx.doi.org/10.1128/mBio.02807-19

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