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EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System
Pathogenic mycobacteria encounter multiple environments during macrophage infection. Temporally, the bacteria are engulfed into the phagosome, lyse the phagosomal membrane, and interact with the cytosol before spreading to another cell. Virulence factors secreted by the mycobacterial ESX-1 (ESAT-6-s...
Autores principales: | Sanchez, Kevin G., Ferrell, Micah J., Chirakos, Alexandra E., Nicholson, Kathleen R., Abramovitch, Robert B., Champion, Matthew M., Champion, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002343/ https://www.ncbi.nlm.nih.gov/pubmed/32019792 http://dx.doi.org/10.1128/mBio.02807-19 |
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