Cargando…

Antiviral activity of iridoid glycosides extracted from Fructus Gardeniae against influenza A virus by PACT-dependent suppression of viral RNA replication

Epidemic and pandemic influenza A virus (IAV) poses a significant threat to human populations worldwide. Iridoid glycosides are principal bioactive components from the Gardenia jasminoides J. Ellis fruit that exhibit antiviral activity against several strains of IAV. In the present study, we evaluat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Shanshan, Bao, Lei, Li, Chun, Sun, Jing, Zhao, Ronghua, Cui, Xiaolan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002373/ https://www.ncbi.nlm.nih.gov/pubmed/32024921 http://dx.doi.org/10.1038/s41598-020-58443-3

Ejemplares similares

Study on Mechanism of Iridoid Glycosides Derivatives from Fructus Gardeniae in Jiangxi Province by Network Pharmacology
por: Liu, Fangzhou, et al.
Publicado: (2020)

Isoflavones' effects on pharmacokinetic profiles of main iridoids from Gardeniae Fructus in rats
por: Chang, Ruirui, et al.
Publicado: (2020)

Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice
por: Niu, Dou, et al.
Publicado: (2021)

An Integrated Analysis Reveals Geniposide Extracted From Gardenia jasminoides J.Ellis Regulates Calcium Signaling Pathway Essential for Influenza A Virus Replication
por: Zhou, Lirun, et al.
Publicado: (2021)

Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia
por: Liu, Zhenhua, et al.
Publicado: (2021)

Multi-omics analysis reveals the molecular basis of flavonoid accumulation in fructus of Gardenia (Gardenia jasminoides Ellis)
por: Chen, Jianrong, et al.
Publicado: (2023)

Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats
por: Tian, Dan-Dan, et al.
Publicado: (2016)

Metabolomics integrated with transcriptomics reveals the distribution of iridoid and crocin metabolic flux in Gardenia jasminoides Ellis
por: Pan, Yuan, et al.
Publicado: (2021)

Effects of Long-Term Administration of Gardeniae Fructus on Intra-Abdominal Organs of Rats
por: Takei, Hisato, et al.
Publicado: (2020)

Mitochondrial-Respiration-Improving Effects of Three Different Gardeniae Fructus Preparations and Their Components
por: Wang, Yun, et al.
Publicado: (2021)

Hypoglycemic, hypolipidemic and antioxidant effects of iridoid glycosides extracted from Corni fructus: possible involvement of the PI3K–Akt/PKB signaling pathway
por: Kang, Jiefang, et al.
Publicado: (2018)

Therapeutic Potential and Effective Components of the Chinese Herb Gardeniae Fructus in the Treatment of Senile Disease
por: Lv, Shichao, et al.
Publicado: (2018)

Investigation of the hemostatic mechanism of Gardeniae fructus Praeparatus based on pharmacological evaluation and network pharmacology
por: Zheng, Yinghao, et al.
Publicado: (2022)

New Lignans and Iridoid Glycosides from Dipsacus asper Wall
por: Sun, Xinguang, et al.
Publicado: (2015)

A New Iridoid Glycoside from the Roots of Dipsacus asper
por: Ji, De, et al.
Publicado: (2012)

Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling
por: Ruan, Jie, et al.
Publicado: (2019)

Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells
por: Li, Chunnan, et al.
Publicado: (2019)

Effects of Multi-Strain Probiotics Combined with Gardeniae fructus on Intestinal Microbiota, Metabolites, and Morphology in Broilers
por: Chang, Chi Huan, et al.
Publicado: (2019)

Determining the Stir-Frying Degree of Gardeniae Fructus Praeparatus Based on Deep Learning and Transfer Learning
por: Zhang, Yuzhen, et al.
Publicado: (2022)

Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation
por: Yang, Cui-cui, et al.
Publicado: (2013)

Cornel Iridoid Glycoside Improves Locomotor Impairment and Decreases Spinal Cord Damage in Rats
por: Tang, Wen-jing, et al.
Publicado: (2016)

Neocornuside A–D, Four Novel Iridoid Glycosides from Fruits of Cornus officinalis and Their Antidiabetic Activity
por: Yang, Meng, et al.
Publicado: (2022)

Phytochemical studies for quantitative estimation of iridoid glycosides in Picrorhiza kurroa Royle
por: Sultan, Phalisteen, et al.
Publicado: (2016)

Study on the chemical reactivity difference of primary hydroxyl groups in iridoid glycosides
por: Kong, Yuanfang, et al.
Publicado: (2023)

Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine
por: Chang, Chiung-Hung, et al.
Publicado: (2013)

Treatment Mechanism of Gardeniae Fructus and Its Carbonized Product Against Ethanol-Induced Gastric Lesions in Rats
por: Zhang, Xue, et al.
Publicado: (2019)

GC-MS Based Metabolomics Reveals the Synergistic Mechanism of Gardeniae Fructus-Forsythiae Fructus Herb Pair in Lipopolysaccharide-Induced Acute Lung Injury Mouse Model
por: Wu, Wenhui, et al.
Publicado: (2021)

Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of Lasianthus verticillatus (Lour.) Merr.
por: Al-Hamoud, Gadah Abdulaziz, et al.
Publicado: (2020)

Two New Iridoid Glycosides from the Root Barks of Sambucus williamsii Hance
por: Wang, Zhen-Yue, et al.
Publicado: (2011)

Two New Iridoid Glycosides from the Root Barks of Sambucus williamsii Hance
por: Kuang, Hai-Xue, et al.
Publicado: (2012)

In Vivo Hepatoprotective and Nephroprotective Activity of Acylated Iridoid Glycosides from Scrophularia hepericifolia
por: Abdel-Kader, Maged S., et al.
Publicado: (2021)

Lipid Nanoparticles Loaded with Selected Iridoid Glycosides as Effective Components of Hydrogel Formulations
por: Dąbrowska, Marta, et al.
Publicado: (2021)

Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis
por: Wang, Ting, et al.
Publicado: (2022)

The Reduction of Tau Hyperphosphorylation by Cornel Iridoid Glycosides Is Mediated by Their Influence on Calpain Activity
por: Guo, Kaiwen, et al.
Publicado: (2022)

Pharmacological systemic analysis of gardenia fructus against non-alcoholic fatty liver disease and validation of animal models
por: Lee, Kang Pa, et al.
Publicado: (2022)

The Rapid and Long-Lasting Antidepressant Effects of Iridoid Fraction in Gardenia Jasminoides J.Ellis Are Dependent on Activating PKA-CREB Signaling Pathway
por: Ren, Li, et al.
Publicado: (2022)

Lipid Nanoparticles Loaded with Iridoid Glycosides: Development and Optimization Using Experimental Factorial Design
por: Dąbrowska, Marta, et al.
Publicado: (2021)

Effects of 5-azaC on Iridoid Glycoside Accumulation and DNA Methylation in Rehmannia glutinosa
por: Dong, Tianyu, et al.
Publicado: (2022)

In vitro characterization of iridoid and phenylethanoid glycosides from Cistanche phelypaea for nutraceutical and pharmacological applications
por: Delicato, Antonella, et al.
Publicado: (2022)

Investigation of Chemical Composition and Biological Activities of Ajuga pyramidalis—Isolation of Iridoids and Phenylethanoid Glycosides
por: Gori, Anthonin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9a2ljqfghase5eejrv0veqj98b