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MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing

The metabolic switch from oxidative phosphorylation to glycolysis is required for tumorigenesis in order to provide cancer cells with energy and substrates of biosynthesis. Therefore, it is important to elucidate mechanisms controlling the cancer metabolic switch. MTR4 is a RNA helicase associated w...

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Detalles Bibliográficos
Autores principales:	Yu, Lili, Kim, Jinchul, Jiang, Lei, Feng, Bingbing, Ying, Yue, Ji, Kai-yuan, Tang, Qingshuang, Chen, Wancheng, Mai, Taoyi, Dou, Wenlong, Zhou, Jianlong, Xiang, Le-yang, He, Yang-fan, Yang, Dinghua, Li, Qingjiao, Fu, Xuemei, Xu, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002374/ https://www.ncbi.nlm.nih.gov/pubmed/32024842 http://dx.doi.org/10.1038/s41467-020-14437-3

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