Cargando…

Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes

The flower of Edgeworthia gardneri (Wall.) Meisn is commonly used in beverage products in Tibet and has potential health benefits for diabetes. However, the mechanisms underlying anti-insulin resistance (IR) action of the flower of E. gardneri are not fully understood. This study aims to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yi, Yan, Li Shan, Ding, Yu, Cheng, Brian Chi Yan, Luo, Gan, Kong, Jing, Liu, Tong Hua, Zhang, Shuo Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002394/ https://www.ncbi.nlm.nih.gov/pubmed/32082162 http://dx.doi.org/10.3389/fphar.2019.01666

Ejemplares similares

The ethanol extract of Edgeworthia gardneri (Wall.) Meisn attenuates macrophage foam cell formation and atherogenesis in ApoE(−/−) mice
por: Tang, Le, et al.
Publicado: (2022)

Edgeworthia gardneri (Wall.) Meisn. extract protects against myocardial infarction by inhibiting NF-κB-and MAPK-mediated endothelial inflammation
por: Wei, Dan, et al.
Publicado: (2022)

Palmitate induces fat accumulation via repressing FoxO1-mediated ATGL-dependent lipolysis in HepG2 hepatocytes
por: Zhao, Naiqian, et al.
Publicado: (2021)

Islet protection and amelioration of type 2 diabetes mellitus by treatment with quercetin from the flowers of Edgeworthia gardneri
por: Zhuang, Manjiao, et al.
Publicado: (2018)

Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2021)

Data on the decreased expression of FOXO1 by miR-1271 in HepG2 hepatocytes
por: Yang, Won-Mo, et al.
Publicado: (2017)

Resveratrol metabolites ameliorate insulin resistance in HepG2 hepatocytes by modulating IRS-1/AMPK
por: Teng, Wendi, et al.
Publicado: (2018)

Coumarins from Edgeworthia chrysantha
por: Li, Xing-Nuo, et al.
Publicado: (2014)

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells
por: Carbajo-Pescador, S, et al.
Publicado: (2013)

Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1
por: Li, Xiu-Dan, et al.
Publicado: (2021)

FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes
por: Tsunekawa, Shin, et al.
Publicado: (2011)

USP10 Alleviates Palmitic Acid-induced Steatosis through Autophagy in HepG2 Cells
por: Xin, Sheng-Liang, et al.
Publicado: (2023)

FoxO1 is a critical regulator of hepatocyte lipid deposition in chronic stress mice
por: Liu, Yun-zi, et al.
Publicado: (2019)

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model
por: Park, Jae-Yeo, et al.
Publicado: (2015)

FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
por: Liang, Chi-Qian, et al.
Publicado: (2022)

The complete chloroplast genome of Edgeworthia chrysantha (Thymelaeaceae)
por: Lee, Shiou Yih, et al.
Publicado: (2020)

Effect of Carotenoids from Phaeodactylum tricornutum on Palmitate-Treated HepG2 Cells
por: Mayer, Claire, et al.
Publicado: (2020)

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells
por: Liu, Jing-Yi, et al.
Publicado: (2019)

Tranilast protects pancreatic β-cells from palmitic acid-induced lipotoxicity via FoxO-1 inhibition
por: Choi, Hye-Eun, et al.
Publicado: (2023)

Differential Inhibite Effect of Xanthohumol on HepG2 Cells and Primary Hepatocytes
por: Zhang, Xiuli, et al.
Publicado: (2022)

Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2
por: Yang, Xuerui, et al.
Publicado: (2009)

Augmentation of Glucotoxicity, Oxidative Stress, Apoptosis and Mitochondrial Dysfunction in HepG2 Cells by Palmitic Acid
por: Alnahdi, Arwa, et al.
Publicado: (2019)

Differential Lipid Accumulation on HepG2 Cells Triggered by Palmitic and Linoleic Fatty Acids Exposure
por: Teixeira, Francisca S., et al.
Publicado: (2023)

FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis
por: Natarajan, Sathish Kumar, et al.
Publicado: (2017)

Pdcd2l Promotes Palmitate-Induced Pancreatic Beta-Cell Apoptosis as a FoxO1 Target Gene
por: Yin, Ye, et al.
Publicado: (2016)

Effects of hyperglycemia on the regulation and expression of the Apoe, Igfbp1 and Foxo1 genes and on nuclear phenotypes in HepG2 cells
por: Ghiraldini, Flávia G, et al.
Publicado: (2013)

Association Study to Evaluate FoxO1 and FoxO3 Gene in CHD in Han Chinese
por: Zhao, Ying, et al.
Publicado: (2014)

Palmitate induces fat accumulation by activating C/EBPβ-mediated G0S2 expression in HepG2 cells
por: Zhao, Nai-Qian, et al.
Publicado: (2017)

Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter
por: Tian, Yu-Nan, et al.
Publicado: (2020)

Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells
por: Cho, Hyunju, et al.
Publicado: (2013)

Data for differentially expressed microRNAs in saturated fatty acid palmitate-treated HepG2 cells
por: Yang, Won-Mo, et al.
Publicado: (2016)

Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
por: Rajan, Priyanka, et al.
Publicado: (2021)

Integrated transcriptome and metabolome analysis unveils the mechanism of color-transition in Edgeworthia chrysantha tepals
por: Zhou, Ningzhi, et al.
Publicado: (2023)

Data on the expression of PEPCK in HepG2 hepatocytes transfected with miR-195
por: Yang, Won-Mo, et al.
Publicado: (2017)

FoxO1 breaks diabetic heart
por: Nagao, Mototsugu, et al.
Publicado: (2013)

Synergy Analysis Reveals Association between Insulin Signaling and Desmoplakin Expression in Palmitate Treated HepG2 Cells
por: Wang, Xuewei, et al.
Publicado: (2011)

Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells
por: Tong, Tuantuan, et al.
Publicado: (2018)

Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2
por: Eynaudi, Andrea, et al.
Publicado: (2021)

Inhibitory Effect of Gardenoside on Free Fatty Acid-Induced Steatosis in HepG2 Hepatocytes
por: Liang, Huiqing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ahaoenpfr1efppnk6mba2voq6r