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Pregnancy and Cancer: the INCIP Project

PURPOSE OF REVIEW: Cancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT FINDINGS: A pregnancy may complicate...

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Autores principales: Maggen, Charlotte, Wolters, Vera E. R. A., Cardonick, Elyce, Fumagalli, Monica, Halaska, Michael J., Lok, Christianne A. R., de Haan, Jorine, Van Tornout, Katrien, Van Calsteren, Kristel, Amant, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002463/
https://www.ncbi.nlm.nih.gov/pubmed/32025953
http://dx.doi.org/10.1007/s11912-020-0862-7
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author Maggen, Charlotte
Wolters, Vera E. R. A.
Cardonick, Elyce
Fumagalli, Monica
Halaska, Michael J.
Lok, Christianne A. R.
de Haan, Jorine
Van Tornout, Katrien
Van Calsteren, Kristel
Amant, Frédéric
author_facet Maggen, Charlotte
Wolters, Vera E. R. A.
Cardonick, Elyce
Fumagalli, Monica
Halaska, Michael J.
Lok, Christianne A. R.
de Haan, Jorine
Van Tornout, Katrien
Van Calsteren, Kristel
Amant, Frédéric
author_sort Maggen, Charlotte
collection PubMed
description PURPOSE OF REVIEW: Cancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT FINDINGS: A pregnancy may complicate diagnostic and therapeutic oncological options, as the unborn child must be protected from potentially hazardous exposures. Pregnant patients should as much as possible be treated as non-pregnant patients, in order to preserve maternal prognosis. Some approaches need adaptations when compared with standard treatment for fetal reasons. Depending on the gestational age, surgery, radiotherapy, and chemotherapy are possible during pregnancy. A multidisciplinary approach is the best guarantee for experience-driven decisions. A setting with a high-risk obstetrical unit is strongly advised to safeguard fetal growth and health. Research wise, the INCIP invests in clinical follow-up of children, as cardiac function, neurodevelopment, cancer occurrence, and fertility theoretically may be affected. Furthermore, parental psychological coping strategies, (epi)genetic alterations, and pathophysiological placental changes secondary to cancer (treatment) are topics of ongoing research. SUMMARY: Further international research is needed to provide patients diagnosed with cancer during pregnancy with the best individualized management plan to optimize obstetrical and oncological care.
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spelling pubmed-70024632020-02-21 Pregnancy and Cancer: the INCIP Project Maggen, Charlotte Wolters, Vera E. R. A. Cardonick, Elyce Fumagalli, Monica Halaska, Michael J. Lok, Christianne A. R. de Haan, Jorine Van Tornout, Katrien Van Calsteren, Kristel Amant, Frédéric Curr Oncol Rep Gynecologic Cancers (NS Reed, Section Editor) PURPOSE OF REVIEW: Cancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT FINDINGS: A pregnancy may complicate diagnostic and therapeutic oncological options, as the unborn child must be protected from potentially hazardous exposures. Pregnant patients should as much as possible be treated as non-pregnant patients, in order to preserve maternal prognosis. Some approaches need adaptations when compared with standard treatment for fetal reasons. Depending on the gestational age, surgery, radiotherapy, and chemotherapy are possible during pregnancy. A multidisciplinary approach is the best guarantee for experience-driven decisions. A setting with a high-risk obstetrical unit is strongly advised to safeguard fetal growth and health. Research wise, the INCIP invests in clinical follow-up of children, as cardiac function, neurodevelopment, cancer occurrence, and fertility theoretically may be affected. Furthermore, parental psychological coping strategies, (epi)genetic alterations, and pathophysiological placental changes secondary to cancer (treatment) are topics of ongoing research. SUMMARY: Further international research is needed to provide patients diagnosed with cancer during pregnancy with the best individualized management plan to optimize obstetrical and oncological care. Springer US 2020-02-05 2020 /pmc/articles/PMC7002463/ /pubmed/32025953 http://dx.doi.org/10.1007/s11912-020-0862-7 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Gynecologic Cancers (NS Reed, Section Editor)
Maggen, Charlotte
Wolters, Vera E. R. A.
Cardonick, Elyce
Fumagalli, Monica
Halaska, Michael J.
Lok, Christianne A. R.
de Haan, Jorine
Van Tornout, Katrien
Van Calsteren, Kristel
Amant, Frédéric
Pregnancy and Cancer: the INCIP Project
title Pregnancy and Cancer: the INCIP Project
title_full Pregnancy and Cancer: the INCIP Project
title_fullStr Pregnancy and Cancer: the INCIP Project
title_full_unstemmed Pregnancy and Cancer: the INCIP Project
title_short Pregnancy and Cancer: the INCIP Project
title_sort pregnancy and cancer: the incip project
topic Gynecologic Cancers (NS Reed, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002463/
https://www.ncbi.nlm.nih.gov/pubmed/32025953
http://dx.doi.org/10.1007/s11912-020-0862-7
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