Cargando…

Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines

To determine whether muscle disuse after a spinal cord injury (SCI) produces elevated markers of cellular senescence and induces markers of the senescence‐associated secretory phenotypes (SASPs) in paralyzed skeletal muscle. Four‐month‐old male Sprague‐Dawley rats received a moderate‐severe (250 kil...

Descripción completa

Detalles Bibliográficos
Autores principales: Graham, Zachary A., Goldberger, Abigail, Azulai, Daniella, Conover, Christine F., Ye, Fan, Bauman, William A., Cardozo, Christopher P., Yarrow, Joshua F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002538/
https://www.ncbi.nlm.nih.gov/pubmed/32026570
http://dx.doi.org/10.14814/phy2.14357