mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion

How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control...

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Detalles Bibliográficos
Autores principales: Gaudette, Brian T., Jones, Derek D., Bortnick, Alexandra, Argon, Yair, Allman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002553/
https://www.ncbi.nlm.nih.gov/pubmed/32024827
http://dx.doi.org/10.1038/s41467-019-14032-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002553/
https://www.ncbi.nlm.nih.gov/pubmed/32024827
http://dx.doi.org/10.1038/s41467-019-14032-1

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