Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism

BACKGROUND: Human mesenchymal stem/stromal cells (hMSCs) represent a promising therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory distress syndrome. Translational challenges include restoring hMSC efficacy following cryopreservation, developing effective xenogeneic-...

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Detalles Bibliográficos
Autores principales: Horie, Shahd, Gaynard, Sean, Murphy, Mary, Barry, Frank, Scully, Michael, O’Toole, Daniel, Laffey, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002627/
https://www.ncbi.nlm.nih.gov/pubmed/32025852
http://dx.doi.org/10.1186/s40635-020-0295-5

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