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Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate
As hyperuricemia is a cause of urate-related diseases such as gout, the anti-hyperuricemic and/or uricosuric activity of food ingredients is receiving increased attention. Here, we examined the inhibitory activities of seven Citrus flavonoids against URAT1, a renal transporter involved in urate re-u...
Autores principales: | Toyoda, Yu, Takada, Tappei, Saito, Hiroki, Hirata, Hiroshi, Ota-Kontani, Ami, Kobayashi, Naoyuki, Tsuchiya, Youichi, Suzuki, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002704/ https://www.ncbi.nlm.nih.gov/pubmed/32047858 http://dx.doi.org/10.1038/s41538-020-0063-7 |
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