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Divergent mutational processes distinguish hypoxic and normoxic tumours

Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and...

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Detalles Bibliográficos
Autores principales:	Bhandari, Vinayak, Li, Constance H., Bristow, Robert G., Boutros, Paul C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002770/ https://www.ncbi.nlm.nih.gov/pubmed/32024819 http://dx.doi.org/10.1038/s41467-019-14052-x

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