Cargando…

Dissecting the role of crosstalk between glioblastoma subpopulations in tumor cell spreading

Glioblastoma (GBM) is a highly infiltrative brain cancer, which is thus difficult to operate. GBM cells frequently harbor Epidermal Growth Factor Receptor amplification (EGFRwt) and/or activating mutation (EGFRvIII), generating at least two different cellular subpopulations within the tumor. We exam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jubran, Maria R., Rubinstein, Ariel M., Cojocari, Irina, Adejumobi, Ibukun Adesoji, Mogilevsky, Maxim, Tibi, Sama, Sionov, Ronit V., Verreault, Maïté, Idbaih, Ahmed, Karni, Rotem, Kravchenko-Balasha, Nataly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002777/ https://www.ncbi.nlm.nih.gov/pubmed/32024816 http://dx.doi.org/10.1038/s41389-020-0199-y

Ejemplares similares

Decoding cancer heterogeneity: studying patient-specific signaling signatures towards personalized cancer therapy
por: Flashner-Abramson, Efrat, et al.
Publicado: (2019)

Drug-Induced Resistance and Phenotypic Switch in Triple-Negative Breast Cancer Can Be Controlled via Resolution and Targeting of Individualized Signaling Signatures
por: Vasudevan, Swetha, et al.
Publicado: (2021)

Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment
por: Mogilevsky, Maxim, et al.
Publicado: (2018)

Overcoming resistance to EGFR monotherapy in HNSCC by identification and inhibition of individualized cancer processes
por: Jubran, Maria R., et al.
Publicado: (2022)

Exploring Alzheimer’s Disease Molecular Variability via Calculation of Personalized Transcriptional Signatures
por: Dagan, Hila, et al.
Publicado: (2020)

Computational quantification and characterization of independently evolving cellular subpopulations within tumors is critical to inhibit anti-cancer therapy resistance
por: Alkhatib, Heba, et al.
Publicado: (2022)

Overcoming resistance to BRAF(V600E) inhibition in melanoma by deciphering and targeting personalized protein network alterations
por: Vasudevan, S., et al.
Publicado: (2021)

Heterogeneity of Gene Expression in Murine Squamous Cell Carcinoma Development—The Same Tumor by Different Means
por: Cohen, Noam, et al.
Publicado: (2013)

Understanding Glioblastoma Signaling, Heterogeneity, Invasiveness, and Drug Delivery Barriers
por: Rabah, Nadin, et al.
Publicado: (2023)

Anomalous Features of EMT during Keratinocyte Transformation
por: Geiger, Tamar, et al.
Publicado: (2008)

Explant Modeling of the Immune Environment of Head and Neck Cancer
por: Sharon, Shay, et al.
Publicado: (2021)

Computational Surprisal Analysis Speeds-Up Genomic Characterization of Cancer Processes
por: Kravchenko-Balasha, Nataly, et al.
Publicado: (2014)

Optimization of Energy-Consuming Pathways towards Rapid Growth in HPV-Transformed Cells
por: Mizrachy-Schwartz, Sarit, et al.
Publicado: (2007)

Convergence of Logic of Cellular Regulation in Different Premalignant Cells by an Information Theoretic Approach
por: Kravchenko-Balasha, Nataly, et al.
Publicado: (2011)

The immunogenic radiation and new players in immunotherapy and targeted therapy for head and neck cancer
por: Sharon, Shay, et al.
Publicado: (2023)

Fact Retrieval and Memory Consolidation for a Movement Sequence: Bidirectional Effects of 'Unrelated' Cognitive Tasks on Procedural Memory
por: Tibi, Rachel, et al.
Publicado: (2013)

2-APB and CBD-Mediated Targeting of Charged Cytotoxic Compounds Into Tumor Cells Suggests the Involvement of TRPV2 Channels
por: Neumann-Raizel, Hagit, et al.
Publicado: (2019)

Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics
por: Lasri, Ayoub, et al.
Publicado: (2020)

Targeting splicing factors for cancer therapy
por: Bashari, Ariel, et al.
Publicado: (2023)

Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes
por: Vessières, Anne, et al.
Publicado: (2021)

MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies
por: Sionov, Ronit Vogt
Publicado: (2013)

Leveling Up the Controversial Role of Neutrophils in Cancer: When the Complexity Becomes Entangled
por: Sionov, Ronit Vogt
Publicado: (2021)

Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer
por: Zahavi, Tamar, et al.
Publicado: (2021)

Paclitaxel Delivery to the Brain for Glioblastoma Treatment
por: AbdEl-haq, Muhammad, et al.
Publicado: (2023)

A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome
por: Sionov, Ronit Vogt, et al.
Publicado: (2023)

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
por: Denichenko, Polina, et al.
Publicado: (2019)

Anti-Microbial Activity of Phytocannabinoids and Endocannabinoids in the Light of Their Physiological and Pathophysiological Roles
por: Sionov, Ronit Vogt, et al.
Publicado: (2022)

Targeting the Holy Triangle of Quorum Sensing, Biofilm Formation, and Antibiotic Resistance in Pathogenic Bacteria
por: Sionov, Ronit Vogt, et al.
Publicado: (2022)

Overexpressed kinetochore genes are used by cancer cells as genome destabilizers and transformation catalysts
por: Aldwaik, Reem Kamal, et al.
Publicado: (2023)

Single-cell transcriptomics of cardiac progenitors reveals functional subpopulations and their cooperative crosstalk in cardiac repair
por: Gao, Lei, et al.
Publicado: (2020)

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist
por: Boccellato, Chiara, et al.
Publicado: (2021)

Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors
por: Sionov, Ronit Vogt, et al.
Publicado: (2022)

Depth Dose Enhancement in Orthovoltage Nanoparticle-Enhanced Radiotherapy: A Monte Carlo Phantom Study
por: Chow, James C. L., et al.
Publicado: (2023)

Regulation of Bim in Health and Disease
por: Sionov, Ronit Vogt, et al.
Publicado: (2015)

Indomethacin sensitizes resistant transformed cells to macrophage cytotoxicity
por: Totary-Jain, Hana, et al.
Publicado: (2016)

Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
por: Itoh, Yasuhiro, et al.
Publicado: (2023)

The regulation of pre-metastatic niche formation by neutrophils
por: Jablonska, Jadwiga, et al.
Publicado: (2017)

Anti-Biofilm Activity of Cannabidiol against Candida albicans
por: Feldman, Mark, et al.
Publicado: (2021)

The Antibacterial Effect of Cannabigerol toward Streptococcus mutans Is Influenced by the Autoinducers 21-CSP and AI-2
por: Aqawi, Muna, et al.
Publicado: (2023)

A Role for Bcl-2 in Notch1-Dependent Transcription in Thymic Lymphoma Cells
por: Sionov, Ronit Vogt, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_365fr50uu10kfk367endcjrvht