Cargando…

SRY-related HMG box-2 role in anaplastic thyroid cancer aggressiveness is related to the fibronectin 1 and PI3K/AKT pathway

Anaplastic thyroid cancer (ATC) is a rare thyroid tumor associated with high mortality rates; thus, the identification of novel molecular targets and the development of therapeutic strategies are urgently required. The present study aimed to investigate the role of SRY-related HMG box-2 (SOX2) in AT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Peng, Shang, Jinbiao, Zhao, Jianqiang, Wang, Kejing, Guo, Liang, Gu, Jialei, Wang, Wendong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002997/ https://www.ncbi.nlm.nih.gov/pubmed/31922212 http://dx.doi.org/10.3892/mmr.2020.10907

Ejemplares similares

RNA binding domain of HDV antigen is homologous to the HMG box of SRY
por: Veretnik, S., et al.
Publicado: (2014)

Expression of SRY-related HMG Box Transcription Factors (Sox) 2 and 9 in Craniopharyngioma Subtypes and Surrounding Brain Tissue
por: Thimsen, Vivian, et al.
Publicado: (2017)

Parathyroid Hormone Reduction Predicts Transient Hypocalcemia after Total Thyroidectomy: A Single-Center Prospective Study
por: Mo, Kangnan, et al.
Publicado: (2020)

Combined expression of the BRAF(V600E) mutation and PD-L1 in early papillary thyroid carcinoma and its relationship with clinicopathological features and recurrence—a retrospective cohort study
por: Zhang, Meili, et al.
Publicado: (2022)

Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal
por: Kaur, Gurpreet, et al.
Publicado: (2010)

HMG-boxes, ribosomopathies and neurodegenerative disease
por: Moss, Tom, et al.
Publicado: (2023)

TERT genetic polymorphism rs2736100 is associated with an aggressive manifestation of papillary thyroid carcinoma
por: Nie, Xilin, et al.
Publicado: (2023)

Circular RNA VANGL1 Facilitates Migration and Invasion of Papillary Thyroid Cancer by Modulating the miR-194/ZEB1/EMT Axis
por: Xiang, Yangfeng, et al.
Publicado: (2022)

Multifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma
por: Zheng, Weihui, et al.
Publicado: (2018)

Comparison of Conventional Open Thyroidectomy and Endoscopic Thyroidectomy via Breast Approach for Papillary Thyroid Carcinoma
por: Tan, Zhuo, et al.
Publicado: (2015)

MiR-345-5p inhibits tumorigenesis of papillary thyroid carcinoma by targeting SETD7
por: Zhao, Ming, et al.
Publicado: (2019)

TOX defines a conserved subfamily of HMG-box proteins
por: O'Flaherty, Emmett, et al.
Publicado: (2003)

The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells
por: Degryse, Bernard, et al.
Publicado: (2001)

A SRY-HMG box frame shift mutation inherited from a mosaic father with a mild form of testicular dysgenesis syndrome in Turner syndrome patient
por: Shahid, Mohammad, et al.
Publicado: (2010)

Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs
por: Kurtz, Stefanie, et al.
Publicado: (2021)

Mitochondrial HMG-Box Containing Proteins: From Biochemical Properties to the Roles in Human Diseases
por: Vozáriková, Veronika, et al.
Publicado: (2020)

Identification of HMG-box family establishes the significance of SOX6 in the malignant progression of glioblastoma
por: Jiang, Lan, et al.
Publicado: (2020)

PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing
por: López-Cánovas, Juan L., et al.
Publicado: (2023)

HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent
por: Kriatchko, Aleksei N, et al.
Publicado: (2008)

A Network of HMG-box Transcription Factors Regulates Sexual Cycle in the Fungus Podospora anserina
por: Ait Benkhali, Jinane, et al.
Publicado: (2013)

Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box
por: Moosa, Mahdi Muhammad, et al.
Publicado: (2018)

Aspirin Inhibits Fibronectin Expression and Reverses Fibronectin-Mediated Cell Invasiveness by Activating Akt Signaling in Preeclampsia
por: Su, Mei-Tsz, et al.
Publicado: (2022)

Fibronectin expression is upregulated by PI-3K/Akt activation in tamoxifen-resistant breast cancer cells
por: You, Daeun, et al.
Publicado: (2017)

Fibronectin 1 inhibits the apoptosis of human trophoblasts by activating the PI3K/Akt signaling pathway
por: Ji, Jinlong, et al.
Publicado: (2020)

The Relationship Between Bullying Victimization and Cyber Aggression Among College Students: The Mediating Effects of Relative Deprivation and Depression
por: Zhang, Jing, et al.
Publicado: (2022)

Identification of SRY‐box 30 as an age‐related essential gatekeeper for male germ‐cell meiosis and differentiation
por: Han, Fei, et al.
Publicado: (2021)

Exportin 4 Interacts with Sox9 through the HMG Box and Inhibits the DNA Binding of Sox9
por: Tsuchiya, Megumi, et al.
Publicado: (2011)

A Unique HMG-Box Domain of Mouse Maelstrom Binds Structured RNA but Not Double Stranded DNA
por: Genzor, Pavol, et al.
Publicado: (2015)

LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway
por: Li, Ding, et al.
Publicado: (2022)

Decreased expression of SRY-box containing gene 30 is related to malignant phenotypes of human bladder cancer and correlates with poor prognosis
por: Liu, Yang, et al.
Publicado: (2018)

O-GlcNAcylation enhances the invasion of thyroid anaplastic cancer cells partially by PI3K/Akt1 pathway
por: Zhang, Peng, et al.
Publicado: (2015)

Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway
por: Pastwińska, Joanna, et al.
Publicado: (2020)

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?
por: Gonzalez-Jimenez, Irene, et al.
Publicado: (2021)

Sry-related High Mobility Group Box 17 Functions as a Tumor Suppressor by Antagonizing the Wingless-related Integration Site Pathway
por: Anani, Maha, et al.
Publicado: (2020)

Corrigendum to: Identification of SRY‐box 30 as an age‐related essential gatekeeper for male germ‐cell meiosis and differentiation
Publicado: (2022)

High affinity binding of proteins HMG1 and HMG2 to semicatenated DNA loops
por: Gaillard, Claire, et al.
Publicado: (2000)

Effects of metformin on the PI3K/AKT/FOXO1 pathway in anaplastic thyroid Cancer cell lines
por: Nozhat, Zahra, et al.
Publicado: (2018)

Restricted expression of oncofetal fibronectin mRNA in thyroid papillary and anaplastic carcinoma: an in situ hybridization study.
por: Takano, T., et al.
Publicado: (1998)

WD Repeat and HMG Box DNA Binding Protein 1: An Oncoprotein at the Hub of Tumorigenesis and a Novel Therapeutic Target
por: Zhang, Zhiwei, et al.
Publicado: (2023)

Comparative studies on microinjected high-mobility-group chromosomal proteins, HMG1 and HMG2
Publicado: (1981)

Cannot write session to /tmp/vufind_sessions/sess_cfdienhqve1st6car0pnumdqqr