Overexpression of TIMP3 inhibits discogenic pain by suppressing angiogenesis and the expression of substance P in nucleus pulposus

Approximately 50% of the cases of low back pain (LBP) are attributed to discogenic origin. The causes of discogenic pain are complicated and consist of a complex biochemical cascade. Neovascularization of intervertebral discs (IVDs) is believed to be associated with discogenic pain. The anti-angioge...

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Detalles Bibliográficos
Autores principales: He, Mingwei, Pang, Jinlei, Sun, Haiyan, Zheng, Guanrong, Lin, Yan, Ge, Weipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003021/
https://www.ncbi.nlm.nih.gov/pubmed/31922222
http://dx.doi.org/10.3892/mmr.2020.10922

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