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miR-21 promotes osteoclastogenesis through activation of PI3K/Akt signaling by targeting Pten in RAW264.7 cells

The present study aimed to investigate the effects of microRNA (miR)-21 on osteoclastogenesis and its underlying molecular mechanisms. The expression levels of tartrate-resistant acid phosphatase (TRAP) and miR-21 were detected during osteoclastogenesis in receptor activator of NF-κB ligand (RANKL)-...

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Detalles Bibliográficos
Autores principales: Wang, Shengli, Liu, Zhigang, Wang, Jingchun, Ji, Xinying, Yao, Zhenqiang, Wang, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003029/
https://www.ncbi.nlm.nih.gov/pubmed/32016444
http://dx.doi.org/10.3892/mmr.2020.10938