Cargando…

Indirubin promotes adipocyte differentiation and reduces lipid accumulation in 3T3-L1 cells via peroxisome proliferator-activated receptor γ activation

The peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in insulin sensitivity and adipocyte differentiation. It is known as ligand-receptor that improves insulin sensitivity in type 2 diabetes mellitus. Several kinds of indigo plant have been already used to treat diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Konno, Taisuke, Sasaki, Kenroh, Kobayashi, Kyoko, Murata, Toshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003043/ https://www.ncbi.nlm.nih.gov/pubmed/32016452 http://dx.doi.org/10.3892/mmr.2020.10946

Ejemplares similares

Paeoniflorin, a constituent of Kami-shoyo-san, suppresses blood glucose levels in postmenopausal diabetic mice by promoting the secretion of estradiol from adipocytes
por: Kobayashi, Kyoko, et al.
Publicado: (2022)

The small molecule indirubin-3′-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity
por: Choi, O M, et al.
Publicado: (2014)

Enhanced 3T3-L1 Differentiation into Adipocytes by Pioglitazone Pharmacological Activation of Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ)
por: Teixeira, Catarina, et al.
Publicado: (2022)

Synthesis and antibacterial activity studies in vitro of indirubin-3′-monoximes
por: Yang, Fen-Fen, et al.
Publicado: (2022)

Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases
por: Blažević, Tina, et al.
Publicado: (2015)

Rifampicin-Induced Hepatic Lipid Accumulation: Association with Up-Regulation of Peroxisome Proliferator-Activated Receptor γ in Mouse Liver
por: Huang, Jia-Hui, et al.
Publicado: (2016)

Bisphenol A is a carcinogen that induces lipid accumulation, peroxisome proliferator‑activated receptor‑γ expression and liver disease
por: Ismael, Layla Qasim, et al.
Publicado: (2022)

An Indirubin Derivative, Indirubin-3′-Monoxime Suppresses Oral Cancer Tumorigenesis through the Downregulation of Survivin
por: Lo, Wan-Yu, et al.
Publicado: (2013)

A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2
por: Takenaka, Yasuhiro, et al.
Publicado: (2013)

Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3′-monoxime
por: Heiss, Elke H., et al.
Publicado: (2016)

Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes
por: Ziqubu, Khanyisani, et al.
Publicado: (2020)

Peroxisome Proliferator-Activated Receptor-γ in Thyroid Autoimmunity
por: Ferrari, Silvia Martina, et al.
Publicado: (2015)

Deoxyschizandrin Loaded Liposomes on the Suppression Lipid Accumulation in 3T3-L1 Adipocytes
por: Liu, Xiaona, et al.
Publicado: (2018)

Effect of nicotinamide N-methyltransferase on lipid accumulation in 3T3-L1 adipocytes
por: Xu, Wanfeng, et al.
Publicado: (2022)

Roles of activin receptor-like kinase 7 signaling and its target, peroxisome proliferator-activated receptor γ, in lean and obese adipocytes
por: Yogosawa, Satomi, et al.
Publicado: (2013)

cis9, trans11-Conjugated Linoleic Acid Differentiates Mouse 3T3-L1 Preadipocytes into Mature Small Adipocytes through Induction of Peroxisome Proliferator-activated Receptor γ
por: Sakuma, Satoru, et al.
Publicado: (2010)

Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and 3T3-L1 adipocytes
por: Pan, Yanyun, et al.
Publicado: (2017)

Apple Flavonols Mitigate Adipocyte Inflammation and Promote Angiogenic Factors in LPS- and Cobalt Chloride-Stimulated Adipocytes, in Part by a Peroxisome Proliferator-Activated Receptor-γ-Dependent Mechanism
por: Liddle, Danyelle M., et al.
Publicado: (2020)

Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation
por: Ohshima, Kousei, et al.
Publicado: (2012)

Peroxisome Proliferator-Activated Receptor-γ Is Critical to Cardiac Fibrosis
por: Liu, Huang-Jun, et al.
Publicado: (2016)

Role of Peroxisome Proliferator-Activated Receptor γ in Ocular Diseases
por: Zhang, Su, et al.
Publicado: (2015)

Effect of peroxisome proliferator-activated receptor γ on inflammatory markers
por: Khazaei, Majid
Publicado: (2015)

The Agonists of Peroxisome Proliferator-Activated Receptor-γ for Liver Fibrosis
por: Li, Jingjing, et al.
Publicado: (2021)

Antioxidant and Anti-Obesity Activities of Polygonum cuspidatum Extract through Alleviation of Lipid Accumulation on 3T3-L1 Adipocytes
por: Choi, Da-Hye, et al.
Publicado: (2020)

Labisia pumila Upregulates Peroxisome Proliferator-Activated Receptor Gamma Expression in Rat Adipose Tissues and 3T3-L1 Adipocytes
por: Mansor, Fazliana, et al.
Publicado: (2013)

Isoflavonoids from Crotalaria albida Inhibit Adipocyte Differentiation and Lipid Accumulation in 3T3-L1 Cells via Suppression of PPAR-γ Pathway
por: Sun, Qinhu, et al.
Publicado: (2015)

Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-Activated Receptor Alpha Network
por: Jun, Hee-Jin, et al.
Publicado: (2012)

Endoplasmic Reticulum Stress Impaired Uncoupling Protein 1 Expression via the Suppression of Peroxisome Proliferator-Activated Receptor γ Binding Activity in Mice Beige Adipocytes
por: Yuliana, Ana, et al.
Publicado: (2019)

Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro
por: Alexander, Stephen PH, et al.
Publicado: (2012)

Antifibrotic effect by activation of peroxisome proliferator-activated receptor–γ in corneal fibroblasts
por: Pan, Hongwei, et al.
Publicado: (2009)

Peroxisome Proliferator-Activated Receptor γ Activity is Required for Appropriate Cardiomyocyte Differentiation
por: Peymani, Maryam, et al.
Publicado: (2016)

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis
por: Benedusi, Valeria, et al.
Publicado: (2012)

Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation
por: Tian, Ye, et al.
Publicado: (2018)

Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes
por: Goto, Tsuyoshi, et al.
Publicado: (2011)

The Alkamide trans-Pellitorine Targets PPARγ via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes
por: Lieder, Barbara, et al.
Publicado: (2017)

Circulating peroxisome proliferator-activated receptor γ is elevated in systemic sclerosis
por: Żółkiewicz, Jakub, et al.
Publicado: (2019)

Correction: Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-Activated Receptor Alpha Network
por: Jun, Hee-Jin, et al.
Publicado: (2012)

Peroxisomal proliferator activated receptor-γ deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3)
por: Francis, Gordon A, et al.
Publicado: (2006)

Pioglitazone increases VEGFR3 expression and promotes activation of M2 macrophages via the peroxisome proliferator-activated receptor γ
por: Zhang, Conghui, et al.
Publicado: (2019)

Pioglitazone, a Peroxisome Proliferator-Activated Receptor γ Agonist, Suppresses Rat Prostate Carcinogenesis
por: Suzuki, Shugo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4vjp8tlk77gggh14bmkh123n3c