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Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan
Increased resistance to environmental stress at the cellular level is correlated with the longevity of long-lived mutants and wild-animal species. Moreover, in experimental organisms, screens for increased stress resistance have yielded mutants that are long-lived. To find entry points for small mol...
Autores principales: | Zhang, Peichuan, Zhai, Yuying, Cregg, James, Ang, Kenny Kean-Hooi, Arkin, Michelle, Kenyon, Cynthia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003076/ https://www.ncbi.nlm.nih.gov/pubmed/31879284 http://dx.doi.org/10.1534/g3.119.400618 |
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