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CRISPR/Cas9-Mediated Integration of Large Transgene into Pig CEP112 Locus

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (Cas9) is a precise genome manipulating tool that can produce targeted gene mutations in various cells and organisms. Although CRISPR/Cas9 can efficiently generate gene knockout, the gene knock-in (KI) efficiency...

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Detalles Bibliográficos
Autores principales:	Li, Guoling, Zhang, Xianwei, Wang, Haoqiang, Mo, Jianxin, Zhong, Cuili, Shi, Junsong, Zhou, Rong, Li, Zicong, Yang, Huaqiang, Wu, Zhenfang, Liu, Dewu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2019
Materias:	Genome Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003105/ https://www.ncbi.nlm.nih.gov/pubmed/31818875 http://dx.doi.org/10.1534/g3.119.400810

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