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MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factors

BACKGROUND: Human enterovirus 71 (EV-A71) is a non-enveloped virus that has a single stranded positive sense RNA genome. In a previous study, we showed that miR-876-5p upregulation was observed in the serum of patients with severe EV-A71 infection. Micro-876-5p (miR-876-5p) is a circulating miRNA th...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Xu, Hwa, Cheng, Hsu Sheng, Chan, Han-Hsiang, Wang, Robert Y. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003331/
https://www.ncbi.nlm.nih.gov/pubmed/32024541
http://dx.doi.org/10.1186/s12985-020-1284-8