Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors

BACKGROUND: Gastrointestinal stromal tumor (GIST) initiation and evolution is commonly framed by KIT/PDGFRA oncogenic activation, and in later stages by the polyclonal expansion of resistant subpopulations harboring KIT secondary mutations after the onset of imatinib resistance. Thus, circulating tu...

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Detalles Bibliográficos
Autores principales: Serrano, César, Vivancos, Ana, López-Pousa, Antonio, Matito, Judit, Mancuso, Francesco M., Valverde, Claudia, Quiroga, Sergi, Landolfi, Stefania, Castro, Sandra, Dopazo, Cristina, Sebio, Ana, Virgili, Anna C., Menso, María M., Martín-Broto, Javier, Sansó, Miriam, García-Valverde, Alfonso, Rosell, Jordi, Fletcher, Jonathan A., George, Suzanne, Carles, Joan, Arribas, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003348/
https://www.ncbi.nlm.nih.gov/pubmed/32024476
http://dx.doi.org/10.1186/s12885-020-6597-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003348/
https://www.ncbi.nlm.nih.gov/pubmed/32024476
http://dx.doi.org/10.1186/s12885-020-6597-x

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