Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors

BACKGROUND: Gastrointestinal stromal tumor (GIST) initiation and evolution is commonly framed by KIT/PDGFRA oncogenic activation, and in later stages by the polyclonal expansion of resistant subpopulations harboring KIT secondary mutations after the onset of imatinib resistance. Thus, circulating tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Serrano, César, Vivancos, Ana, López-Pousa, Antonio, Matito, Judit, Mancuso, Francesco M., Valverde, Claudia, Quiroga, Sergi, Landolfi, Stefania, Castro, Sandra, Dopazo, Cristina, Sebio, Ana, Virgili, Anna C., Menso, María M., Martín-Broto, Javier, Sansó, Miriam, García-Valverde, Alfonso, Rosell, Jordi, Fletcher, Jonathan A., George, Suzanne, Carles, Joan, Arribas, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003348/
https://www.ncbi.nlm.nih.gov/pubmed/32024476
http://dx.doi.org/10.1186/s12885-020-6597-x

Ejemplares similares

Ejemplares similares