Cargando…

Bone health in symptomatic carriers of haemophilia A: a protocol for a multicentre prospective matched-cohort study

INTRODUCTION: Haemophilia A is an X linked inherited bleeding disorder, caused by a decrease in coagulation factor VIII. Persons with haemophilia experience repeated musculoskeletal bleeding, which can lead to decreased range of motion, irreversible joint damage, low bone mineral density (BMD), and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Grace H, Norris, Erin, Petrucci, Jessica, James, Paula D, Lee, Adrienne, Poon, Man-Chiu, Floros, Georgina, Boma-Fischer, Laurence, Teitel, Jerry, Nisenbaum, Rosane, Sholzberg, Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Haematology (Incl Blood Transfusion)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003383/ https://www.ncbi.nlm.nih.gov/pubmed/31796490 http://dx.doi.org/10.1136/bmjopen-2019-032891

Ejemplares similares

PHILEOS (haemoPHILia and ostEoporOSis) Study: protocol of a multicentre prospective case–control study
por: Tardy‐Poncet, Brigitte, et al.
Publicado: (2021)

Desmopressin treatment combined with clotting factor VIII concentrates in patients with non-severe haemophilia A: protocol for a multicentre single-armed trial, the DAVID study
por: Schütte, Lisette M, et al.
Publicado: (2019)

Assessment of global coagulation function under treatment with emicizumab concomitantly with bypassing agents in haemophilia A with inhibitor (UNEBI Study): multicentre open-label non-randomised clinical trial
por: Ogiwara, Kenichi, et al.
Publicado: (2022)

Twelve-month prevalence of haemarthrosis and joint disease using the Haemophilia Joint Health score: evaluation of the UK National Haemophilia Database and Haemtrack patient reported data: an observational study
por: Wilkins, Richard A, et al.
Publicado: (2022)

Determinants of adherence and consequences of the transition from adolescence to adulthood among young people with severe haemophilia (TRANSHEMO): study protocol for a multicentric French national observational cross-sectional study
por: Resseguier, Noémie, et al.
Publicado: (2018)

AKATSUKI study: a prospective, multicentre, phase IV study evaluating the safety of emicizumab under and immediately after immune tolerance induction therapy in persons with congenital haemophilia A with factor VIII inhibitors
por: Matsushita, Tadashi, et al.
Publicado: (2022)

AOZORA: long-term safety and joint health in paediatric persons with haemophilia A without factor VIII inhibitors receiving emicizumab – protocol for a multicentre, open-label, phase IV clinical study
por: Shima, Midori, et al.
Publicado: (2022)

Study protocol for assessment of the coagulation potential of concomitantly used factor VIII concentrates in patients with haemophilia A with emicizumab prophylaxis (CAGUYAMA Study): a multicentre open-label non-randomised clinical trial
por: Takeyama, Masahiro, et al.
Publicado: (2023)

DosEmi study protocol: a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia A
por: Donners, Anouk, et al.
Publicado: (2023)

Health-related quality of life of patients with haemophilia: a cross-sectional survey in the Northeast of China
por: Niu, Jinyu, et al.
Publicado: (2022)

Exploration of the impact of gene therapy on the lives of people with haemophilia and their families: a protocol for the mixed-methods exigency study
por: Fletcher, Simon, et al.
Publicado: (2022)

Protocol for a feasibility randomised controlled trial of a musculoskeletal exercise intervention versus usual care for children with haemophilia
por: Hashem, Ferhana, et al.
Publicado: (2019)

Pharmacokinetics and complementary evaluation system-based guidance on prophylaxis of paediatric patients with haemophilia A in China with Kovaltry: protocol of the LEAP study
por: Kun, Huang, et al.
Publicado: (2021)

Design of the HEM-POWR study: a prospective, observational study of real-world treatment with damoctocog alfa pegol in patients with haemophilia A
por: Sanabria, Martin, et al.
Publicado: (2021)

Design of a prospective observational study on the effectiveness and real-world usage of recombinant factor VIII Fc (rFVIIIFc) compared with conventional products in haemophilia A: the A-SURE study
por: Oldenburg, Johannes, et al.
Publicado: (2019)

Effectiveness of two psychological interventions for pain management, emotional regulation and promotion of quality of life among adult Portuguese men with haemophilia (PSY-HaEMOPEQ): study protocol for a single-centre prospective randomised controlled trial
por: Pinto, Patrícia Ribeiro, et al.
Publicado: (2017)

Gender disparities in red blood cell transfusion in elective surgery: a post hoc multicentre cohort study
por: Gombotz, Hans, et al.
Publicado: (2016)

Developing a supportive and palliative care intervention for patients with allogeneic stem cell transplantation: protocol of a multicentre mixed-methods study (allo-PaS)
por: Pralong, Anne, et al.
Publicado: (2023)

Assessing the impact on intestinal microbiome and clinical outcomes of antibiotherapy optimisation strategies in haematopoietic stem cell transplant recipients: study protocol for the prospective multicentre OptimBioma study
por: Jiménez-Jorge, Silvia, et al.
Publicado: (2020)

Protocol for a multicentre, parallel-group, open-label randomised controlled trial comparing ferric carboxymaltose with the standard of care in anaemic Malawian pregnant women: the REVAMP trial
por: Mwangi, Martin N, et al.
Publicado: (2021)

Accuracy of efficient data methods to determine the incidence of hospital-acquired thrombosis and major bleeding in medical and surgical inpatients: a multicentre observational cohort study in four UK hospitals
por: Horner, Daniel, et al.
Publicado: (2023)

Trial protocol: a multicentre randomised trial of first-line treatment pathways for newly diagnosed immune thrombocytopenia: standard steroid treatment versus combined steroid and mycophenolate. The FLIGHT trial
por: Pell, Julie, et al.
Publicado: (2018)

Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials)
por: Reade, Michael C., et al.
Publicado: (2022)

Time to detection of anaemia and its predictors among women of reproductive-age living with HIV/AIDS initiating ART at public hospitals, Southwest Ethiopia: a multicentre retrospective follow-up study
por: Belay, Alemayehu Sayih, et al.
Publicado: (2022)

Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study)
por: Lasocki, Sigismond, et al.
Publicado: (2021)

MUKtwelve protocol: a phase II randomised, controlled, open, parallel group, multicentre trial of selinexor, cyclophosphamide and prednisolone (SCP) versus cyclophosphamide and prednisolone (CP) in patients with relapsed or refractory multiple myeloma
por: Kendall, Jessica, et al.
Publicado: (2022)

Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia
por: Muñoz Builes, Mario, et al.
Publicado: (2020)

Multicentre, open-label, randomised controlled clinical trial to assess the efficacy and safety of appropriate target values for lipid management in patients who have mild-to-moderate stenotic lesions with high-risk plaques in coronary arteries: study protocol
por: Matsuda, Morihiro, et al.
Publicado: (2019)

Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia
por: Barber, Vicki S, et al.
Publicado: (2023)

Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT: to WiN study
por: Heijdra, Jessica M, et al.
Publicado: (2022)

Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I–II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21)
por: Sakaguchi, Hirotoshi, et al.
Publicado: (2023)

Protocol description of the HOVON 141/VISION trial: a prospective, multicentre, randomised phase II trial of ibrutinib plus venetoclax in patients with creatinine clearance ≥30 mL/min who have relapsed or refractory chronic lymphocytic leukaemia (RR-CLL) with or without TP53 aberrations
por: Levin, Mark-David, et al.
Publicado: (2020)

Point-of-care washing of allogeneic red blood cells for the prevention of transfusion-related respiratory complications (WAR-PRC): a protocol for a multicenter randomised clinical trial in patients undergoing cardiac surgery
por: Warner, Matthew A, et al.
Publicado: (2017)

Risk Factors for Alloimmunisation after red blood Cell Transfusions (R-FACT): a case cohort study
por: Zalpuri, Saurabh, et al.
Publicado: (2012)

Patient self-assessment of hospital pain, mood and health-related quality of life in adults with sickle cell disease
por: Anie, Kofi A, et al.
Publicado: (2012)

Assessment of whole body MRI and sestamibi technetium-99m bone marrow scan in prediction of multiple myeloma disease progression and outcome: a prospective comparative study
por: Khalafallah, Alhossain A, et al.
Publicado: (2013)

Stem cell transplantation of matched sibling donors compared with immunosuppressive therapy for acquired severe aplastic anaemia: a Cochrane systematic review
por: Peinemann, Frank, et al.
Publicado: (2014)

Current practice of venous thromboembolism prevention in acute trusts: a qualitative study
por: McFarland, L, et al.
Publicado: (2014)

An audit of anticoagulant management to assess anticoagulant control using decision support software
por: Harper, Paul, et al.
Publicado: (2014)

Randomised controlled trial of weekly chloroquine to re-establish normal erythron iron flux and haemoglobin recovery in postmalarial anaemia
por: Cox, Sharon E, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0i3qm3tbsub45car6i2egtddet