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Intra-arterial versus standard intravenous administration of lutetium-177-DOTA-octreotate in patients with NET liver metastases: study protocol for a multicenter, randomized controlled trial (LUTIA trial)
BACKGROUND: Lutetium-177-DOTA-octreotate ((177)Lu-DOTATATE) significantly increases survival and response rates in patients with grade I and grade II neuroendocrine tumors (NETs). However, survival and response rates are significantly lower in patients with bulky liver metastases. Increasing the tum...
Autores principales: | Ebbers, Sander C., Braat, Arthur J. A. T., Moelker, Adriaan, Stokkel, Marcel P. M., Lam, Marnix G. E. H., Barentsz, Maarten W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003409/ https://www.ncbi.nlm.nih.gov/pubmed/32024533 http://dx.doi.org/10.1186/s13063-019-3888-0 |
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