Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes

BACKGROUND: Astrocytes are the most abundant glial cells in a brain that mediate inflammatory responses and provide trophic support for neurons. We have previously disclosed that paroxetine, a common selective serotonin reuptake inhibitor, ameliorates LPS-induced microglia activation. However, it re...

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Detalles Bibliográficos
Autores principales: Zhang, Xiong, Zhu, Lan-Bing, He, Jia-Hui, Zhang, Hong-Qiu, Ji, Shu-Ya, Zhang, Chao-Nan, Hou, Na-Na, Huang, Chen-Ping, Zhu, Jian-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003432/
https://www.ncbi.nlm.nih.gov/pubmed/32024542
http://dx.doi.org/10.1186/s12974-020-1712-0

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