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Redox status, DNA and HSA binding study of naturally occurring naphthoquinone derivatives
In the present work we modified the procedure for isolation of naphthoquinones α-methylbutyrylshikon (1), acetylshikonin (2) and β-hydroxyisovalerylshikonin (3) from Onosma visianii Clem. We also investigated possible mechanisms of 1, 2 and 3 as antitumor agents. Accordingly, we estimated concentrat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003638/ https://www.ncbi.nlm.nih.gov/pubmed/32038116 http://dx.doi.org/10.17179/excli2019-1859 |