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Redox status, DNA and HSA binding study of naturally occurring naphthoquinone derivatives

In the present work we modified the procedure for isolation of naphthoquinones α-methylbutyrylshikon (1), acetylshikonin (2) and β-hydroxyisovalerylshikonin (3) from Onosma visianii Clem. We also investigated possible mechanisms of 1, 2 and 3 as antitumor agents. Accordingly, we estimated concentrat...

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Detalles Bibliográficos
Autores principales: Vukic, Milena D., Vukovic, Nenad L., Obradovic, Ana, Matic, Milos, Djukic, Maja, Avdovic, Edina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003638/
https://www.ncbi.nlm.nih.gov/pubmed/32038116
http://dx.doi.org/10.17179/excli2019-1859