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5,6,7,4’-Tetramethoxyflavanone protects against neuronal degeneration induced by dexamethasone by attenuating amyloidogenesis in mice
Long-term exposure to high glucocorticoid levels induces memory impairment and neurodegeneration in Alzheimer's disease (AD) by increasing the expression of amyloid β and tau hyperphosphorylation (pTau). Previous studies showed beneficial effects of flavonoids in neurodegenerative models. 5,6,7...
Autores principales: | Pakdeepak, Kanet, Chokchaisiri, Ratchanaporn, Tocharus, Jiraporn, Jearjaroen, Pranglada, Tocharus, Chainarong, Suksamrarn, Apichart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003641/ https://www.ncbi.nlm.nih.gov/pubmed/32038114 http://dx.doi.org/10.17179/excli2019-1940 |
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