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BATCAVE: calling somatic mutations with a tumor- and site-specific prior
Detecting somatic mutations withins tumors is key to understanding treatment resistance, patient prognosis and tumor evolution. Mutations at low allelic frequency, those present in only a small portion of tumor cells, are particularly difficult to detect. Many algorithms have been developed to detec...
Autores principales: | Mannakee, Brian K, Gutenkunst, Ryan N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003682/ https://www.ncbi.nlm.nih.gov/pubmed/32051931 http://dx.doi.org/10.1093/nargab/lqaa004 |
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