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Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review

BACKGROUND: Ependymomas, especially intracranial ependymomas, are rare neoplasms of the CNS. The clinical courses of patients with intracranial ependymomas can be quite variable. At present, data on parkinsonism caused by ependymomas are scarce. CASE PRESENTATION: A 13‐year‐old girl presented with p...

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Detalles Bibliográficos
Autores principales: Lou, Yue, Wang, Yanwen, Zhuang, Liying, Cai, Miao, Liu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003710/
https://www.ncbi.nlm.nih.gov/pubmed/32055763
http://dx.doi.org/10.1002/agm2.12093
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author Lou, Yue
Wang, Yanwen
Zhuang, Liying
Cai, Miao
Liu, Xiaoli
author_facet Lou, Yue
Wang, Yanwen
Zhuang, Liying
Cai, Miao
Liu, Xiaoli
author_sort Lou, Yue
collection PubMed
description BACKGROUND: Ependymomas, especially intracranial ependymomas, are rare neoplasms of the CNS. The clinical courses of patients with intracranial ependymomas can be quite variable. At present, data on parkinsonism caused by ependymomas are scarce. CASE PRESENTATION: A 13‐year‐old girl presented with parkinsonism symptoms of clumsiness in her left leg and hand. Her mother was diagnosed with Parkinson's disease at age 30, nine years previously. Magnetic resonance imaging showed a lesion in the temporal lobe with long‐T1 signal, mixed‐T2 signal. The patient was taken in for a right tumorectomy and was diagnosed as having an ependymoma postoperatively. The patient's symptoms fully resolved in the postoperative phase. CONCLUSION: The case describes the mechanism of intracranial ependymoma involving parkinsonism symptoms. Our findings suggest that in some patients presenting with atypical PD symptoms the underlying cause should not be overlooked; MRI examination is necessary.
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spelling pubmed-70037102020-02-13 Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review Lou, Yue Wang, Yanwen Zhuang, Liying Cai, Miao Liu, Xiaoli Aging Med (Milton) Case Reports BACKGROUND: Ependymomas, especially intracranial ependymomas, are rare neoplasms of the CNS. The clinical courses of patients with intracranial ependymomas can be quite variable. At present, data on parkinsonism caused by ependymomas are scarce. CASE PRESENTATION: A 13‐year‐old girl presented with parkinsonism symptoms of clumsiness in her left leg and hand. Her mother was diagnosed with Parkinson's disease at age 30, nine years previously. Magnetic resonance imaging showed a lesion in the temporal lobe with long‐T1 signal, mixed‐T2 signal. The patient was taken in for a right tumorectomy and was diagnosed as having an ependymoma postoperatively. The patient's symptoms fully resolved in the postoperative phase. CONCLUSION: The case describes the mechanism of intracranial ependymoma involving parkinsonism symptoms. Our findings suggest that in some patients presenting with atypical PD symptoms the underlying cause should not be overlooked; MRI examination is necessary. John Wiley and Sons Inc. 2019-12-27 /pmc/articles/PMC7003710/ /pubmed/32055763 http://dx.doi.org/10.1002/agm2.12093 Text en © 2019 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Lou, Yue
Wang, Yanwen
Zhuang, Liying
Cai, Miao
Liu, Xiaoli
Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title_full Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title_fullStr Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title_full_unstemmed Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title_short Parkinsonism caused by Intracranial ependymoma: A rare case report and literature review
title_sort parkinsonism caused by intracranial ependymoma: a rare case report and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003710/
https://www.ncbi.nlm.nih.gov/pubmed/32055763
http://dx.doi.org/10.1002/agm2.12093
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