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No evidence for cell‐to‐cell transmission of the unfolded protein response in cell culture

The unfolded protein response (UPR) is one of the major cell‐autonomous proteostatic stress responses. The UPR has been implicated in the pathogenesis of neurodegenerative diseases and is therefore actively investigated as therapeutic target. In this respect, cell non‐autonomous effects of the UPR i...

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Detalles Bibliográficos
Autores principales: van Ziel, Anna M., Wolzak, Kimberly, Nölle, Anna, Hoetjes, Petrus J., Berenjeno‐Correa, Ernesto, van Anken, Eelco, Struys, Eduard A., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003778/
https://www.ncbi.nlm.nih.gov/pubmed/31442299
http://dx.doi.org/10.1111/jnc.14856