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Outcomes of different aortic arch replacement techniques

BACKGROUND: Consensus on the best treatment for aortic arch pathology is unresolved due to an emerging variety of procedures. We aimed to compare the outcomes of two major techniques for open aortic arch replacement involving the supra‐aortic branches and to identify the risk factors for specific ad...

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Autores principales: Abjigitova, Djamila, Mokhles, Mostafa M., Papageorgiou, Grigorios, Bekkers, Jos A., Bogers, Ad J.J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003787/
https://www.ncbi.nlm.nih.gov/pubmed/31816120
http://dx.doi.org/10.1111/jocs.14386
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author Abjigitova, Djamila
Mokhles, Mostafa M.
Papageorgiou, Grigorios
Bekkers, Jos A.
Bogers, Ad J.J.C.
author_facet Abjigitova, Djamila
Mokhles, Mostafa M.
Papageorgiou, Grigorios
Bekkers, Jos A.
Bogers, Ad J.J.C.
author_sort Abjigitova, Djamila
collection PubMed
description BACKGROUND: Consensus on the best treatment for aortic arch pathology is unresolved due to an emerging variety of procedures. We aimed to compare the outcomes of two major techniques for open aortic arch replacement involving the supra‐aortic branches and to identify the risk factors for specific adverse events. METHODS: Between 1974 and 2017, 172 patients were treated with either the en bloc (island, n = 59; 34.3%) or branched graft technique (n = 113, 65.7%). Most of the patients were treated in an emergent/urgent setting (52.4%). RESULTS: Patients who underwent the en bloc procedure had significantly shorter cardiopulmonary bypass (median: 241 vs 271 minutes, P = .041) and aortic cross clamp times (median: 124 vs 168 minutes, P = .005) than patients who underwent the separate graft technique. Overall, the hospital mortality was lower in the en bloc group, 8.5% vs 19.5%, although the difference was not significant (P = .077). No difference was found in the survival between the separate graft and en bloc groups at 1 (77.0 vs 86.3%), 5 (67.7 vs 66.3%) and 10 years (42.4 vs 51.3%), (P = .63). The postoperative stroke rate was comparable between the en bloc and separate graft cohorts (14.3 vs 19.6%, P = .52). Diabetics and those who underwent an elephant trunk procedure were at a higher risk for reintervention. CONCLUSIONS: The separate graft technique, which is more common today, showed no difference from the en bloc technique with regard to hospital mortality and morbidity. Furthermore, the late survival and reintervention rates were similar after both procedures.
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spelling pubmed-70037872020-02-10 Outcomes of different aortic arch replacement techniques Abjigitova, Djamila Mokhles, Mostafa M. Papageorgiou, Grigorios Bekkers, Jos A. Bogers, Ad J.J.C. J Card Surg Original Articles BACKGROUND: Consensus on the best treatment for aortic arch pathology is unresolved due to an emerging variety of procedures. We aimed to compare the outcomes of two major techniques for open aortic arch replacement involving the supra‐aortic branches and to identify the risk factors for specific adverse events. METHODS: Between 1974 and 2017, 172 patients were treated with either the en bloc (island, n = 59; 34.3%) or branched graft technique (n = 113, 65.7%). Most of the patients were treated in an emergent/urgent setting (52.4%). RESULTS: Patients who underwent the en bloc procedure had significantly shorter cardiopulmonary bypass (median: 241 vs 271 minutes, P = .041) and aortic cross clamp times (median: 124 vs 168 minutes, P = .005) than patients who underwent the separate graft technique. Overall, the hospital mortality was lower in the en bloc group, 8.5% vs 19.5%, although the difference was not significant (P = .077). No difference was found in the survival between the separate graft and en bloc groups at 1 (77.0 vs 86.3%), 5 (67.7 vs 66.3%) and 10 years (42.4 vs 51.3%), (P = .63). The postoperative stroke rate was comparable between the en bloc and separate graft cohorts (14.3 vs 19.6%, P = .52). Diabetics and those who underwent an elephant trunk procedure were at a higher risk for reintervention. CONCLUSIONS: The separate graft technique, which is more common today, showed no difference from the en bloc technique with regard to hospital mortality and morbidity. Furthermore, the late survival and reintervention rates were similar after both procedures. John Wiley and Sons Inc. 2019-12-09 2020-02 /pmc/articles/PMC7003787/ /pubmed/31816120 http://dx.doi.org/10.1111/jocs.14386 Text en © 2019 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Abjigitova, Djamila
Mokhles, Mostafa M.
Papageorgiou, Grigorios
Bekkers, Jos A.
Bogers, Ad J.J.C.
Outcomes of different aortic arch replacement techniques
title Outcomes of different aortic arch replacement techniques
title_full Outcomes of different aortic arch replacement techniques
title_fullStr Outcomes of different aortic arch replacement techniques
title_full_unstemmed Outcomes of different aortic arch replacement techniques
title_short Outcomes of different aortic arch replacement techniques
title_sort outcomes of different aortic arch replacement techniques
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003787/
https://www.ncbi.nlm.nih.gov/pubmed/31816120
http://dx.doi.org/10.1111/jocs.14386
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