NF‐E2‐related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin‐1 mutated Alzheimer's disease astrocytes

Alzheimer's disease (AD) is a common dementia affecting a vast number of individuals and significantly impairing quality of life. Despite extensive research in animal models and numerous promising treatment trials, there is still no curative treatment for AD. Astrocytes, the most common cell ty...

Descripción completa

Detalles Bibliográficos
Autores principales: Oksanen, Minna, Hyötyläinen, Ida, Trontti, Kalevi, Rolova, Taisia, Wojciechowski, Sara, Koskuvi, Marja, Viitanen, Matti, Levonen, Anna‐Liisa, Hovatta, Iiris, Roybon, Laurent, Lehtonen, Šárka, Kanninen, Katja M., Hämäläinen, Riikka H., Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003860/
https://www.ncbi.nlm.nih.gov/pubmed/31670864
http://dx.doi.org/10.1002/glia.23741

Ejemplares similares

Ejemplares similares