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A TLR7 agonist strengthens T and NK cell function during BRAF‐targeted therapy in a preclinical melanoma model
Therapeutic success of targeted therapy with BRAF inhibitors (BRAFi) for melanoma is limited by resistance development. Observations from preclinical mouse models and recent insights into the immunological effects caused by BRAFi give promise for future development of combination therapy for human m...
Autores principales: | Bellmann, Lydia, Cappellano, Giuseppe, Schachtl‐Riess, Johanna F., Prokopi, Anastasia, Seretis, Athanasios, Ortner, Daniela, Tripp, Christoph H., Brinckerhoff, Constance E., Mullins, David W., Stoitzner, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003881/ https://www.ncbi.nlm.nih.gov/pubmed/31702822 http://dx.doi.org/10.1002/ijc.32777 |
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