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Assisted delivery of anti-tumour platinum drugs using DNA-coiling gold nanoparticles bearing lumophores and intercalators: towards a new generation of multimodal nanocarriers with enhanced action
New gold and lipoic based nanocarriers for the delivery of platinum(ii) and platinum(iv) drugs are developed, which allow enhanced loading of the drug on the surface of the nanocarriers and release in a pH-dependent fashion, with superior release at lower pHs which are associated with many tumours....
Autores principales: | Caballero, Ana B., Cardo, Lucia, Claire, Sunil, Craig, James S., Hodges, Nikolas J., Vladyka, Anton, Albrecht, Tim, Rochford, Luke A., Pikramenou, Zoe, Hannon, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003971/ https://www.ncbi.nlm.nih.gov/pubmed/32055309 http://dx.doi.org/10.1039/c9sc02640a |
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