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Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients

BACKGROUND: Premature skin aging results from exposure to a range of environmental factors, primarily ultraviolet radiation, but also high‐energy visible light in the blue spectrum, infrared radiation, and environmental pollution. These extrinsic factors result in the generation of reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Bernstein, Eric F., Sarkas, Harry W., Boland, Patricia, Bouche, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004163/
https://www.ncbi.nlm.nih.gov/pubmed/31134729
http://dx.doi.org/10.1111/jocd.13007
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author Bernstein, Eric F.
Sarkas, Harry W.
Boland, Patricia
Bouche, Deborah
author_facet Bernstein, Eric F.
Sarkas, Harry W.
Boland, Patricia
Bouche, Deborah
author_sort Bernstein, Eric F.
collection PubMed
description BACKGROUND: Premature skin aging results from exposure to a range of environmental factors, primarily ultraviolet radiation, but also high‐energy visible light in the blue spectrum, infrared radiation, and environmental pollution. These extrinsic factors result in the generation of reactive oxygen species which promote photoaging and DNA damage resulting in skin cancers. AIMS: To formulate skincare products utilizing a new coating applied to zinc oxide and titanium dioxide particles and complimentary skincare ingredients to provide broad protection against a range of environmental insults. METHODS: A cross‐polymer, multifunctional coating of silicate, polyalkylsilsesquioxane, and polydimethylsiloxane moieties increases the photostability and decreases the reactivity of mineral sunscreen agents when interacting with energy sources. These products are also formulated with antioxidants to minimize free radical propagation. Additionally, this coating improves the esthetic feel of mineral sunscreens, while the appearance is enhanced by formulating products with a blend of iron oxides. RESULTS: A series of in vitro and ex vivo studies demonstrated the ability of mineral‐based products formulated with the new multifunctional coating to provide protection against ultraviolet radiation, high‐energy visible light, infrared radiation, and environmental pollution. CONCLUSION: Newly formulated mineral‐based skincare products provide environmental protection, are ecologically safe, and can replace chemical‐based sunscreen ingredients.
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spelling pubmed-70041632020-02-11 Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients Bernstein, Eric F. Sarkas, Harry W. Boland, Patricia Bouche, Deborah J Cosmet Dermatol Skin Care Articles BACKGROUND: Premature skin aging results from exposure to a range of environmental factors, primarily ultraviolet radiation, but also high‐energy visible light in the blue spectrum, infrared radiation, and environmental pollution. These extrinsic factors result in the generation of reactive oxygen species which promote photoaging and DNA damage resulting in skin cancers. AIMS: To formulate skincare products utilizing a new coating applied to zinc oxide and titanium dioxide particles and complimentary skincare ingredients to provide broad protection against a range of environmental insults. METHODS: A cross‐polymer, multifunctional coating of silicate, polyalkylsilsesquioxane, and polydimethylsiloxane moieties increases the photostability and decreases the reactivity of mineral sunscreen agents when interacting with energy sources. These products are also formulated with antioxidants to minimize free radical propagation. Additionally, this coating improves the esthetic feel of mineral sunscreens, while the appearance is enhanced by formulating products with a blend of iron oxides. RESULTS: A series of in vitro and ex vivo studies demonstrated the ability of mineral‐based products formulated with the new multifunctional coating to provide protection against ultraviolet radiation, high‐energy visible light, infrared radiation, and environmental pollution. CONCLUSION: Newly formulated mineral‐based skincare products provide environmental protection, are ecologically safe, and can replace chemical‐based sunscreen ingredients. John Wiley and Sons Inc. 2019-05-28 2020-02 /pmc/articles/PMC7004163/ /pubmed/31134729 http://dx.doi.org/10.1111/jocd.13007 Text en © 2019 The Authors. Journal of Cosmetic Dermatology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Skin Care Articles
Bernstein, Eric F.
Sarkas, Harry W.
Boland, Patricia
Bouche, Deborah
Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title_full Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title_fullStr Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title_full_unstemmed Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title_short Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
title_sort beyond sun protection factor: an approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredients
topic Skin Care Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004163/
https://www.ncbi.nlm.nih.gov/pubmed/31134729
http://dx.doi.org/10.1111/jocd.13007
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