Induction of systemic immunity through nasal-associated lymphoid tissue (NALT) of mice intranasally immunized with Brucella abortus malate dehydrogenase-loaded chitosan nanoparticles

Infection with Brucella abortus causes contagious zoonosis, brucellosis, and leads to abortion in animals and chronic illness in humans. Chitosan nanoparticles (CNs), biocompatible and nontoxic polymers, acts as a mucosal adjuvant. In our previous study, B. abortus malate dehydrogenase (Mdh) was loa...

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Detalles Bibliográficos
Autores principales: Shim, Soojin, Soh, Sang Hee, Im, Young Bin, Ahn, Choonghyun, Park, Hong-Tae, Park, Hyun-Eui, Park, Woo Bin, Kim, Suji, Yoo, Han Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004331/
https://www.ncbi.nlm.nih.gov/pubmed/32027689
http://dx.doi.org/10.1371/journal.pone.0228463

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