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Improved cell-specificity of adeno-associated viral vectors for medullary thyroid carcinoma using calcitonin gene regulatory elements

Targeted gene therapy using recombinant adeno-associated virus (rAAV) vectors is a potential therapeutic strategy for treating cancer, and tissue-specific promoters may help with tissue targeting. Medullary thyroid carcinoma (MTC) is a disease of the calcitonin secreting thyroid C cells, and calcito...

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Detalles Bibliográficos
Autores principales:	Levy, Hazel C., Hulvey, Danielle, Adamson-Small, Laura, Jn-Simon, Natacha, Prima, Victor, Rivkees, Scott, Hobbs, Jacqueline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004351/ https://www.ncbi.nlm.nih.gov/pubmed/32027681 http://dx.doi.org/10.1371/journal.pone.0228005

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