Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma

The NOTCH2 gene plays a role in the development of many tumors. Deltex E3 ubiquitin ligase 3 (DTX3) was identified as a novel E3 ligase for NOTCH2 and as a potential therapeutic target for esophageal cancer. However, whether DTX3 could regulate NOTCH2 to suppress the progression of esophageal carcin...

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Detalles Bibliográficos
Autores principales: Ding, Xin‐Yu, Hu, Hai‐Yang, Huang, Ke‐Nan, Wei, Rong‐Qiang, Min, Jie, Qi, Chen, Tang, Hua, Qin, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004520/
https://www.ncbi.nlm.nih.gov/pubmed/31854042
http://dx.doi.org/10.1111/cas.14288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004520/
https://www.ncbi.nlm.nih.gov/pubmed/31854042
http://dx.doi.org/10.1111/cas.14288

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