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GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor‐suppressor gene TGFβR2 in colorectal cancer

Chromosome 7q (Ch.7q) is clonally amplified in colorectal cancer (CRC). We aimed to identify oncogenes on Ch.7q that are overexpressed through DNA copy number amplification and determine the biological and clinical significance of these oncogenes in CRC. We identified general transcription factor 2I...

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Detalles Bibliográficos
Autores principales: Nambara, Sho, Masuda, Takaaki, Kobayashi, Yuta, Sato, Kuniaki, Tobo, Taro, Koike, Kensuke, Noda, Miwa, Ogawa, Yushi, Kuroda, Yousuke, Ito, Shuhei, Eguchi, Hidetoshi, Sugimachi, Keishi, Mimori, Koshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004548/
https://www.ncbi.nlm.nih.gov/pubmed/31758608
http://dx.doi.org/10.1111/cas.14248