First‐in‐human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

Fibroblast growth factor receptors (FGFR) are a family of transmembrane receptor tyrosine kinases involved in regulating cellular processes. FGFR mutations are implicated in oncogenesis, representing therapeutic potential in the form of FGFR inhibitors. This phase I, first‐in‐human study in Japan ev...

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Detalles Bibliográficos
Autores principales: Koyama, Takafumi, Shimizu, Toshio, Iwasa, Satoru, Fujiwara, Yutaka, Kondo, Shunsuke, Kitano, Shigehisa, Yonemori, Kan, Shimomura, Akihiko, Iizumi, Sakura, Sasaki, Tatsuya, Furuse, Junji, Yamamoto, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004556/
https://www.ncbi.nlm.nih.gov/pubmed/31797489
http://dx.doi.org/10.1111/cas.14265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004556/
https://www.ncbi.nlm.nih.gov/pubmed/31797489
http://dx.doi.org/10.1111/cas.14265

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