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Platelet inhibitory activity, tolerability, and safety of vicagrel, a novel thienopyridine P2Y12 inhibitor

Vicagrel is a new antiplatelet pro-drug based on clopidogrel sulfur lactone metabolites. The purpose of the study was to evaluate the safety, tolerability, and pharmacodynamics (PD) of vicagrel in healthy Chinese subjects. This study was designed as a single-center, randomized, double-blind, placebo...

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Detalles Bibliográficos
Autores principales: Li, Hui, Chen, Hanjing, Chen, Weili, Xu, Hongrong, Yuan, Fei, Yang, Mengjie, Sun, Hongbin, Yang, Jin, Liu, Yongqiang, Lai, Xiaojuan, Gong, Yanchun, Liu, Xuefang, Li, Yongguo, Sheng, Lei, Liu, Chao, Li, Xuening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004678/
https://www.ncbi.nlm.nih.gov/pubmed/31977858
http://dx.doi.org/10.1097/MD.0000000000018683