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Platelet inhibitory activity, tolerability, and safety of vicagrel, a novel thienopyridine P2Y12 inhibitor
Vicagrel is a new antiplatelet pro-drug based on clopidogrel sulfur lactone metabolites. The purpose of the study was to evaluate the safety, tolerability, and pharmacodynamics (PD) of vicagrel in healthy Chinese subjects. This study was designed as a single-center, randomized, double-blind, placebo...
Autores principales: | Li, Hui, Chen, Hanjing, Chen, Weili, Xu, Hongrong, Yuan, Fei, Yang, Mengjie, Sun, Hongbin, Yang, Jin, Liu, Yongqiang, Lai, Xiaojuan, Gong, Yanchun, Liu, Xuefang, Li, Yongguo, Sheng, Lei, Liu, Chao, Li, Xuening |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004678/ https://www.ncbi.nlm.nih.gov/pubmed/31977858 http://dx.doi.org/10.1097/MD.0000000000018683 |
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