A long-term retrospective study on sporadic Burkitt lymphoma in chinese population

Burkitt lymphoma (BL), an aggressive malignancy, brings a prognosis varying among children, adolescents, and adults. Most of previous retrospective studies of BL focused on a part of population. This study aimed to find the leading prognostic factors in BL among patients of different age groups. Wor...

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Autores principales: Yang, Xiaoyun, Huang, Qianru, Li, An, Chen, Yuan, Xu, Wei, Li, Jianyong, Wang, Yaping, Fang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
4800
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004692/
https://www.ncbi.nlm.nih.gov/pubmed/32000356
http://dx.doi.org/10.1097/MD.0000000000018438
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author Yang, Xiaoyun
Huang, Qianru
Li, An
Chen, Yuan
Xu, Wei
Li, Jianyong
Wang, Yaping
Fang, Yongjun
author_facet Yang, Xiaoyun
Huang, Qianru
Li, An
Chen, Yuan
Xu, Wei
Li, Jianyong
Wang, Yaping
Fang, Yongjun
author_sort Yang, Xiaoyun
collection PubMed
description Burkitt lymphoma (BL), an aggressive malignancy, brings a prognosis varying among children, adolescents, and adults. Most of previous retrospective studies of BL focused on a part of population. This study aimed to find the leading prognostic factors in BL among patients of different age groups. World Health Organization classification of lymphoid neoplasms in 2008 and revision in 2016 were used as diagnostic criteria for BL. We compared the laboratory results and clinical manifestations in 2 age groups by Kaplan–Meier survival analysis. Our study strongly indicated that age >14 years and lactate dehydrogenase >570 U/L were 2 powerful prognostic factors for BL. The results indicated that poor prognosis may be for the poor tolerance and low dose of drugs in adolescents and adults.
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spelling pubmed-70046922020-02-18 A long-term retrospective study on sporadic Burkitt lymphoma in chinese population Yang, Xiaoyun Huang, Qianru Li, An Chen, Yuan Xu, Wei Li, Jianyong Wang, Yaping Fang, Yongjun Medicine (Baltimore) 4800 Burkitt lymphoma (BL), an aggressive malignancy, brings a prognosis varying among children, adolescents, and adults. Most of previous retrospective studies of BL focused on a part of population. This study aimed to find the leading prognostic factors in BL among patients of different age groups. World Health Organization classification of lymphoid neoplasms in 2008 and revision in 2016 were used as diagnostic criteria for BL. We compared the laboratory results and clinical manifestations in 2 age groups by Kaplan–Meier survival analysis. Our study strongly indicated that age >14 years and lactate dehydrogenase >570 U/L were 2 powerful prognostic factors for BL. The results indicated that poor prognosis may be for the poor tolerance and low dose of drugs in adolescents and adults. Wolters Kluwer Health 2020-01-31 /pmc/articles/PMC7004692/ /pubmed/32000356 http://dx.doi.org/10.1097/MD.0000000000018438 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4800
Yang, Xiaoyun
Huang, Qianru
Li, An
Chen, Yuan
Xu, Wei
Li, Jianyong
Wang, Yaping
Fang, Yongjun
A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title_full A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title_fullStr A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title_full_unstemmed A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title_short A long-term retrospective study on sporadic Burkitt lymphoma in chinese population
title_sort long-term retrospective study on sporadic burkitt lymphoma in chinese population
topic 4800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004692/
https://www.ncbi.nlm.nih.gov/pubmed/32000356
http://dx.doi.org/10.1097/MD.0000000000018438
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