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In situ structure determination at nanometer resolution using TYGRESS
The resolution of subtomogram averages calculated from cryo-electron tomograms (cryo-ET) of crowded cellular environments is often limited due to signal-loss in, and misalignment of the subtomograms. In contrast, single-particle cryo-electron microscopy (SP-cryo-EM) routinely reaches near-atomic res...
Autores principales: | Song, Kangkang, Shang, Zhiguo, Fu, Xiaofeng, Lou, Xiaochu, Grigorieff, Nikolaus, Nicastro, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004880/ https://www.ncbi.nlm.nih.gov/pubmed/31768058 http://dx.doi.org/10.1038/s41592-019-0651-0 |
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